Abstract #1245
Multimodal determination of load changes in the muscle - A combination of 1 H-MEGA-PRESS and blood sampling
Kevin Tschiesche 1 , Alexander Gussew 1 , Maria Glckner 2 , Steffen Derlien 2 , and Jrgen R Reichenbach 1
1
Medical Physics Group, Institute of
Diagnostic and Interventional Radiology, Jena University
Hospital - Friedrich Schiller University Jena, Jena,
Germany,
2
Institute
for Physiotherapy, Jena University Hospital - Friedrich
Schiller University Jena, Jena, Germany
In the current study we monitored and directly compared
local and global lactate changes in healthy volunteers
by means of 1H MEGA-PRESS MRS and blood sampling,
respectively, that were induced by exercising the calf
muscle. Normalized ratios of lactate to creatine
(Lac/Cr) as well as blood lactate concentrations both
increased after the exercise indicating high anaerobic
exercise conditions. However, different decay time
constants of lactate were observed in muscle and blood,
which can be ascribed to subsequent processes affecting
the blood lactate time courses within the tissue.
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