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Abstract #1282

Functional network interactions during typical development in infancy and early childhood

Jonathan O'Muircheartaigh 1,2 , Douglas C Dean 3 , Lindsay Walker 4 , Nicole Waskiewicz 4 , Holly Dirks 4 , and Sean Deoni 4,5

1 Department of Neuroimaging, King's College London, London, United Kingdom, 2 Centre for the Developing Brain, King's College London, London, London, United Kingdom, 3 Waisman Center, University of Wisconsin-Madison, Wisconsin, United States, 4 School of Engineering, Brown University, Rhode Island, United States, 5 Department of Pediatric Radiology, Children's Hospital Colorado, Denver, Colorado, United States

We report on cross-sectional study interrogating coupling between functional networks using resting-state fMRI in a technically challenging group, infants and young children aged 3 months to 5 years. We investigate the relationship between coupling between these functional networks and maturity. In addition we also interrogate the relationship between cognitive ability and connectivity. We demonstrate extensive positive and negative relationships in coupling between resting state functional networks, the relationship with cognitive ability is subtle and restricted. These results add to the growing literature on functional network interactions during development.

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