The Use of Magnetic Resonance Spectroscopy in the Evaluation of Epilepsy in Pediatric Patients
Marisa Blitstein 1 , Sandra Rincon 1 , Paul Caruso 1 , Ronald Thibert 2 , Ramon Gilberto Gonzalez 1,3 , and Eva-Maria Ratai 1,3
Department of Radiology, Neuroradiology
Division, Massachusetts General Hospital, Harvard
Medical School, Boston, MA, United States,
/ Pediatric Neurology, Massachusetts General Hospital,
Harvard Medical School, Boston, MA, United States,
A. Martinos Center for Biomedical Imaging, MA, United
The purpose of our study was to retrospectively evaluate
MRI, MRS, and clinical data to determine how often MRS
added information to conventional MRI for evaluation of
seizure in pediatric patients. A database search between
1/1/2011 and 12/31/2013 to identify patients <18 years
old with both MRI and MRS for evaluation of seizure
resulted in 241 cases. In our series, MRS yielded
additional information for 40% (96/241) of all patients.
The largest subsets of patients that had MRS exams
yielding additional information were patients with
hypoxic ischemic injury, distinguishing dysplasia from
neoplasm, and prompting metabolic or genetics workup.
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