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Abstract #1444

Preliminary study of hypoxic exposure effect on cerebral blood perfusion of pilots using 3D ASL

Jie Liu 1 , Wanshi Zhang 2 , Long Qian 3 , Mingxi Liu 1 , Xianrong Xu 2 , and Limin Meng 2

1 The Fourth Military Medical University, Xi'an, Shanxi, China, 2 Air Force General Hospital, Beijing, China, 3 GE Healthcare China, Beijing, China

Pilots often need to face and overcome hypoxia at upper atmosphere due to low oxygen concentration and low pressure. In this study we mimicked hypoxic environment equal to 3000m altitude and obtained the CBF of the participant pilots before and after hypoxic exposure using 3D pcASL. Lower CBF values were observed in pilots after hypoxic exposure in various regions, mostly happened at right hemisphere, which might be due to that the right one is more involved in visual-space and the right hemisphere was sensitive to hypoxia, which may be related to the pilots professional characteristics

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