Multi-b-value diffusion weighted imaging acquired on a 3T MR scanner: comparison of the apparent diffusion coefficient in prostate cancer detection and the contribution of b-value images in ADC map interpretation.
Thomas de Perrot 1 , Bndicte M A Delattre 1 , Lindsey A Crowe 1 , Iris Friedli 1 , Marc Pusztaszeri 2 , Jean-Christophe Tille 2 , Christophe Iselin 3 , and Jean-Paul Valle 1
Division of Radiology, Geneva University
Hospital, Geneva, Switzerland,
of Clinical Pathology, Geneva University Hospital,
of Urologic Surgery, Geneva University Hospital, Geneva,
We examined the influence of b-value on ADC map
performance for prostate cancer in a retrospective
study. We have demonstrated that the flow-sensitive ADC
map was superior to the flow-insensitive ADC map for
prostate cancer detection and that multi-b ADC maps in
comparison with a 2-b ADC map did not improve detection.
In addition, b-value images provide complementary
information and improve over the ADC map alone in cancer
detection. This study provides a statistical
demonstration of the commonly accepted practice to look
for enhanced signal in cancer on the high b-values
images in the area of reduced ADC.
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