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Abstract #1542

Characterisation of Placental Diffusion in Twin Pregnancies using Diffusion-Weighted Magnetic Resonance Imaging

Soha Said Ramadan 1 , Pablo Caro Dominguez 1,2 , Jorge H. Davila 1,2 , Melissa Valdez Quintana 1,2 , Julie Hurteau-Miller 1,2 , David Grynspan 2,3 , Felipe Moretti 2,4 , and Elka Miller 1,2

1 Department of Radiology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada, 2 Department of Diagnostic Imaging, University of Ottawa, Ottawa, Ontario, Canada, 3 Department of Pathology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada, 4 Department of Obstetrics, Gynecology and Newborn Care, The Ottawa Hospital, Ottawa, Ontario, Canada

INTRODUCTION: Most fetal DWI studies investigate singletons or rare twin-related diseases. This retrospective study investigates twin placental diffusion. METHODS: Two ADC-quantification methods were evaluated. Diffusion was compared within twins with double-disc placentas and between twins and normal singletons. RESULTS: ADC-quantification methods were significantly different. No significant diffusion difference was found within double-disc placental pairs or between twins and singletons with GA≤24 weeks. Comparison for GA>24 weeks could not be performed due to data paucity. DISCUSSION: Quantification discrepancy suggests non-uniform placental diffusion. Results suggest no twin-placental diffusion difference within twins or compared to singletons with GA≤24 weeks. Pathological correlation is required.

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