Robust and Noninvasive Measurement of Renal Perfusion using Multi-Phase Pseudo-Continuous Arterial Spin Labeling
William Jeffrey Triffo 1 and Youngkyoo Jung 2
Department of Radiology, Wake Forest School
of Medicine, Winston Salem, NC, United States,
of Radiology and Biomedical Engineering, Wake Forest
School of Medicine, Winston Salem, NC, United States
The accuracy of pseudo-continuous ASL (PCASL) methods is
sensitive to phase errors related to off-resonance
effects at the tagging plane. Respiratory motion is also
a well-known problem in body imaging. We present the
application of multi-phase PCASL (MP-PCASL) to study
renal perfusion, along with a masked object registration
algorithm for semi-automatic alignment after breath-hold
acquisition. Example data illustrating off-resonance
induced errors in the PCASL estimation of renal blood
flow and the associated phase errors are provided.
MP-PCASL provides a robust alternative that is
insensitive to such errors.
This abstract and the presentation materials are available to members only;
a login is required.