Abstract #1583
Accurate quantification of blood perfusion in the kidney using pseudo-continuous arterial spin labelling: an optimisation and reproducibility study
Susie Clarke 1 , James F Meaney 1 , and Andrew J Fagan 1
1
National Centre for Advanced Medical Imaging
(CAMI), St. James's Hospital / Trinity College Dublin,
Dublin 8, Ireland
The measurement of blood perfusion in the kidney using a
non-contrast approach was investigated. A protocol was
optimised using pseudo-continuous arterial spin
labelling coupled with a TSE readout, and the
reproducibility of the resulting measurements assessed
in a healthy cohort. A spatial resolution of
2.5x2.5x6mm3 was obtained with an SNR of 563, allowing
for separation of cortex and medulla regions in the
calculated perfusion maps. Mean perfusion values of
29344 / 13920 ml/100g/min were measured in the
cortex/medulla respectively, with good intra- and
inter-session reproducibility. Good breath-hold
tolerance reported by the volunteers suggests that
clinical implementation is feasible.
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