Abstract #1752
Retrospective motion correction in CEST MRI data using time domain analysis
Nirbhay N. Yadav 1,2 , Kannie W. Y. Chan 1,2 , Monica Pearl 1 , Piotr Walczak 1 , Miroslaw Janowski 1,3 , Peter C. M. van Zijl 1,2 , and Michael T. McMahon 1,2
1
The Russell H. Morgan Department of
Radiology and Radiological Science, The Johns Hopkins
University, Baltimore, MD, United States,
2
FM
Kirby Research Center, Kennedy Krieger Institute,
Baltimore, MD, United States,
3
NeuroRepair
Department, MMRC, PAS, Warsaw, Poland
Abdominal motion has limited the number CEST MRI studies
in the body since signal fluctuations can be an order of
magnitude larger than the CEST signal. Using simulated
data and also data from experiments where arginine
capsules where injected into live swine, we show how
motion effects in z-spectra can be significantly reduced
retrospectively using time-domain analysis.
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