Intra-voxel incoherent motion modelling of diffusion weighted MRI data is feasible in 5 minutes scan time
Oliver Gurney-Champion 1,2 , Martijn Froeling 3 , Remy Klaassen 4,5 , Hanneke W.M. van Laarhoven 4 , Jaap Stoker 1 , Arjan Bel 2 , and Aart J. Nederveen 1
Radiology, Academic Medical Center,
Oncology, Academic Medical Center, Amsterdam,
University Medical Center Utrecht, Utrecht, Netherlands,
of Medical Oncology, Academic Medical Center, Amsterdam,
for Experimental Oncology and Radiobiology, Academic
Medical Center, Amsterdam, Netherlands
Measurements suitable for intra-voxel incoherent motion
(IVIM) modelling of diffusion weighted (DW) MRI take
long (>10 minutes) as multiple averages and diffusion
weightings are measured. To determine the minimal
measurement time, we investigated how IVIM in the liver
and pancreas performs as function of measurement time.
We measured DW-MRI (9 averages, 14 b-values) in 16
healthy volunteers twice in two sessions. During post
processing we deleted measurements to assess the
performance as function of averages and b-values. We
find that IVIM can be done roboustly in 5 minutes using
5 averages and 12 b-values.
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