Abstract #3313
iHARPERELLA: an improved method for integrated 3D phase unwrapping and background phase removal
Wei Li 1,2 , Bing Wu 3 , and Chunlei Liu 4,5
1
Research Imaging Institute, University of
Texas Health Science Center at San Antonio, San Antonio,
TX, United States,
2
Ophthalmology,
University of Texas Health Science Center at San
Antonio, San Antonio, TX, United States,
3
GE
Healthcare, Beijing, China,
4
Brain
Imaging and Analysis Center, Duke University, Durham,
NC, United States,
5
Radiology,
Duke University, Durham, NC, United States
Quantitative susceptibility mapping requires reliable 3D
phase unwrapping and background phase removal.
Previously, we have developed a method for integrated 3D
phase unwrapping and harmonic background phase removal
using Laplacian, namely HARPERELLA. In this study, we
introduced an improved version of this HARPERELLA
method, which allows more intuitive implementation and
more robust suppression of the low frequency background
phase. Importantly, it also provides the selection
between smooth phase throughout the field of view or
intact local phase variations around the veins by
choosing between Laplacian-based and path-based phase
unwrapping.
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