Abstract #3476
Optimized vascular signal reduction in contrast enhanced 3D T1 Turbo Spin Echo Imaging
Neville D Gai 1 and John A Butman 1
1
Radiology & Imaging Sciences, NIH, Bethesda,
MD, United States
Contrast enhanced MRI (CE-MRI)of the brain is routinely
used to identify lesions and for staging treatment
therapy. 3D T1-w turbo spin-echo (TSE) sequence provides
a valuable contrast mechanism. However, identification
of contrasting tissue can be hampered by neighboring
enhancing vascular signal (VS). Typically, a preparation
sequence is used to reduce the vascular signal. In this
work, we study the application of vascular crushing
gradients (VCG) along all axes integrated into the 3D T1
TSE sequence to reduce enhancing vasculature. Such a
sequence is advantageous in reducing scan time as well
as providing continuous reduction in VS. Evaluation of
VS in CE-MRI images showed a large reduction in VS with
a minor reduction in SNR after introduction of VCG.
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