Abstract #3603
Hybridized arterial spin labeled MR angiography in the evaluation of carotid artery stenosis in patients with suspected stroke: Preliminary analysis and comparison to gadolinium-enhanced MR angiography
Kai Xu 1 , LeRoy Stromberg 1 , David Rusinak 1 , Stephen Futterer 1 , Shivraman Giri 1 , James Carr 1 , Robert Edelman 1 , Ioannis Koktzoglou 2 , and Jeremy Collins 1
1
Radiology, Northwestern University, Chicago,
IL, United States,
2
Radiology,
NorthShore University HealthSystem, Evanston, IL, United
States
Carotid artery atherosclerosis is an important etiology
of stroke, for which morphological assessment with
quantitation of luminal narrowing plays a critical role
in diagnosis and mangement. However, contrast-enhanced
MRA and contrast-enhanced CTA are contraindicated in
patients with stage 4 or 5 renal insufficiency due to
the risk of nephrogenic systemic fibrosis and iodinated
contrast induced nephropathy. hASL is a non-contrast MR
angiographic technique which has shown promise for
neurovascular assessment. In a prospective patient
cohort with suspected stroke, hASL MRA excluded carotid
artery stenosis as an etiology, demonstrating excellent
agreement with contrast-enhanced MRA.
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