Abstract #3901
Default Mode Network Abnormality in ADHD Rat Model
Sheng-Min Huang 1 , Wei-Cheng Lee 1 , Kung-Chu Ho 2 , and Fu-Nien Wang 1
1
Department of Biomedical Engineering &
Environmental Sciences, National Tsing Hua University,
Hsinchu, Taiwan,
2
Nuclear
Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Resting state functional MRI is an emerging neuroimaging
method, examining the connectivity of brain neural
circuits. In this work a seed-based analysis was carried
out to compare the resting state network between normal
(WKY) and ADHD rat model (SHR). Results show that ADHD
rat presented a network contains caudate putamen region
but WKY didn't. This difference may be tied to the
symptoms of ADHD since putamen is involved in the
regulation of motor behavior and caudate nucleus is
related to social behavior.
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