Abstract #3930
Overlapping functional networks subserving single-digit multiplication
Joe S. Cheng 1,2 , Iris Y. Zhou 1,2 , Mengye Lyu 1,2 , and Ed X. Wu 1,2
1
Laboratory of Biomedical Imaging and Signal
Processing, The University of Hong Kong, Hong Kong, Hong
Kong, China,
2
Department
of Electrical and Electronic Engineering, The University
of Hong Kong, Hong Kong, China
Modern neuroimaging techniques, especially fMRI, have
advanced our understanding of the neuroanatomical basis
of cognitive processes such as mental arithmetic. Most
studies so far only attempted to relate individual
activated regions with specific processes. However, the
neural activation within a given region may reflect the
summation of multiple distinct networks that carry
different functional purposes. By combining general
linear model (GLM) and independent components analysis
(ICA) into contributive source analysis (CSA), this
study aimed to test the hypothesis that multiple
functional networks engage in simple mental task of
single-digit multiplication and contribute collectively
to the activations in prefrontal and parietal cortices.
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