Abstract #4419
Robust Detection of Axonal Abnormalities in High School Collision-Sport Athletes: Longitudinal Single Subject Analysis
Ikbeom Jang 1 , Il Yong Chun 1 , Larry J. Leverenz 2 , Eric A. Nauman 3,4 , and Thomas M. Talavage 1,4
1
School of Electrical & Computer Engineering,
Purdue Universisty, West Lafayatte, Indiana, United
States,
2
Department
of Health & Kinesiology, Purdue Universisty, Indiana,
United States,
3
School
of Mechanical Engineering, Purdue Universisty, Indiana,
United States,
4
Weldon
School of Biomedical Engineering, Purdue Universisty,
Indiana, United States
Using diffusion-weighted MR imaging, a single
subject-based approach is proposed here to detect
athletes exhibiting longitudinal deviations in
fractional anisotropy (FA) as observed by paired
tract-based spatial statistics (TBSS). High-school aged
male football and female soccer athletes were scanned
longitudinally three times during the course of a
competition season, during which they experienced
multiple collisions to the head or whiplash-like
acceleration events. Significant increases in FA were
observed in the second half of the season, relative to
the pre-season measures, for most asymptomatic soccer
players.
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