1Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, 2Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of
Fat fraction of the bone marrow has been suggested as an important
quantitative parameter in the assessment of treatment response and
determination of the benignity in oncologic imaging. Therefore, accurate fat
quantification is a prerequisite for the fat fraction to be established as a
reliable imaging biomarker. For this purpose, spoiled gradient echo sequences
have been commonly used. However, gradient echo imaging is susceptible to B0
variations from various sources such as respiration, cardiac pulsation. In this
study, we investigate and compensate the effects of respiration-induced B0
variations on fat quantification of the bone marrow in the lumbar spine.
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