Non-contrast Pulmonary Perfusion at 3T using FAIR with inflow saturation and background suppression
Joshua S. Greer1,2, Yue Zhang2, Christopher Maroules2, Orhan K. Oz2, Ivan Pedrosa2,3, and Ananth J. Madhuranthakam2,3
1Bioengineering, University of Texas at Dallas, Richardson, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States
Flow Alternating Inversion Recovery (FAIR) has been studied
extensively for pulmonary perfusion imaging at 1.5T, but suffers from low SNR,
and is often corrupted by bright signal in the major vasculature and image
misregistration artifacts due to respiratory motion. The purpose of this study was to evaluate FAIR at 3T for increased SNR and compare against SPECT perfusion, to combine FAIR with inflow saturation to reduce signal in the major pulmonary
vessels, and to combine FAIR with background suppression strategies to minimize
artifacts due to image misregistration.
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