Lukas Reinhold Buschle1, Felix Tobias Kurz1,2, Thomas Kampf3, Heinz-Peter Schlemmer1, and Christian Herbert Ziener1
1E010 Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 2Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany, 3Department of Experimental Physics 5, University of Würzburg, Würzburg, Germany
In lung tissue, the susceptibility difference
between air-filled alveoli and surrounding tissue causes a strong dephasing of
spin-bearing particles. The particles experience an
averaged magnetic field due to diffusion effects. Thus, the dephasing process slows down. Both diffusion and susceptibility effects are described by the Bloch-Torrey
equation that is solved for the local magnetization on the surface of alveoli.
The analytical solution of the free induction decay is compared to in vivo measurements in human lung
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