Abstract #2992

Applying „Electric Properties Tomography“ to Low Frequency Conductivity Using Magnetic Particle Imaging

Ulrich Katscher¹, Jürgen Rahmer¹, Christian Stehning¹, Peter Vernickel¹, and Bernhard Gleich¹

¹Philips Research Europe, Hamburg, Germany

MRI-based “Electric Properties Tomography” (MRI-EPT) determines electric conductivity measuring and post-processing the spatial distribution of the TX RF field. Obtained conductivity corresponds to Larmor frequency, reflecting biochemical content of tissue, but not its specific cellular structure. Cellular tissue structure is reflected by conductivity at low frequency (LF, 100-500 kHz), as used for “Magnetic Particle Imaging” (MPI). Similar to MRI, MPI is able to determine the spatial distribution of applied LF field, and thus, a reconstruction of LF conductivity should be possible (“MPI-EPT”) in analogy to MRI-EPT. This study investigated the principle feasibility of MPI-EPT and compared results with MRI-EPT.

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