Xilun Ma1, Jitian Guan1, Zhiyan Zhang1, Miaomiao Chen1, Yanzi Chen1, Zhiwei Shen1, and Renhua Wu1
1Department of Medical Imaging, the 2nd Affiliated Hospital, Medical College of Shantou University, Shantou 515041, China, Shantou, China, People's Republic of
Parkinson Disease’s (PD) patients and four healthy controls(HC) underwent the
diffusional kurtosis imaging (DKI) and then we tested the PD’s patients with Hoehn-Yahr scale and Unified Parkinson Disease Rating Scale(UPDRS). As a result, we found a significant decrease of Mean kurtosis (MK) values in the left substantia
nigra between PD’s patients and healthy controls. Moreover, the kurtosis
fractional anisotropy (KFA) values in right red nucleus of the PD’s patients
were positively associated with the UPDRS
scores in our study.