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Abstract #3944

31P MR Imaging and Concentration Measurements

Arthur Coste1, Alexandre Vignaud1, Philippe Ciuciu1,2, Fawzi Boumezbeur1, Franck Mauconduit3, Alexis Amadon1, Sandro Romanzetti4, Denis Le Bihan1, and C├ęcile Lerman1

1MR Imaging and Spectroscopy Unit, NeuroSpin, Gif sur Yvette, France, 2Parietal, INRIA Saclay, Saclay, France, 3Siemens Healthcare, Saint Denis, France, 4University Clinic RWTH Aachen, Aachen, Germany

This work describes a novel method accounting for MR acquisition properties (B0, B1+,B1-,T1,T2*) to perform concentration measurements in the framework of in vitro Phosphorus MRI. Our pipeline uses a non-Cartesian 3D sequence for efficient signal sampling and a wavelet regularized least square method for reconstruction. We demonstrated within an acceptable time for human experiment, for 5mm isotropic resolution, that we are able to calibrate and measure absolute 31P concentrations.

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