Abstract #3945

Mapping of sodium and water content ratio in vivo in the human calf

Anja M. Marschar¹, Moritz C. Berger¹, Mark E. Ladd¹, Peter Bachert¹, and Armin M. Nagel^1,2

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Diagnostic and Interventional Radiology, University Medical Center Ulm, Ulm, Germany

Both lower legs of three male healthy volunteers were examined at 3 T and 7 T by means of ¹H and ²³Na MRI to obtain quantitative maps of the sodium and water content in muscle tissue. Corrections for T₂^* and T₁ relaxation and RF profiles (B₁⁺, B₁^–) were performed. The resulting water content value in calf muscle tissue was in the range of 75–85 mol/l, the level of sodium was 15–21 mmol/l (sodium-to-water content ratio: 0.20–0.27 ‰).

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