Abstract #4175

Slip interface imaging: a novel MR-elastography based imaging method for assessing the surgical plane of cleavage in meningiomas

Ziying Yin¹, Kevin J. Glaser¹, Armando Manduca², Jamie J. Van Gompel³, Arvin Arani¹, Joshua D. Hughes³, Anthony Romano⁴, Richard L. Ehman¹, and John Huston III¹

¹Radiology, Mayo Clinic, Rochester, MN, United States, ²Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States, ³Neurosurgery, Mayo Clinic, Rochester, MN, United States, ⁴Naval Research Laboratory, Washington, WA, United States

The preoperative assessment of the surgical cleavage plane at the tumor-brain interface in meningiomas is important for surgical planning. A recently developed slip interface imaging (SII) technique is uniquely capable of directly assessing the degree of tumor adherence at the tumor-brain interface. In this study, SII was applied to assess the surgical cleavage plane between the tumor and the underlying brain in meningiomas. The correlation between the SII results and the surgical plane of cleavage was statistically significant (p=0.0014). The presence of a complete slip interface suggests the tumor can be removed using a dissection plane outside the pia mater.

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