Xiaozhi Cao1, Congyu Liao1, Zhixing Wang1, Huihui Ye1, Ying Chen1, Hongjian He1, Song Chen1, Hui Liu2, and Jianhui Zhong1
1Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou,Zhejiang, China, People's Republic of, 2MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China, People's Republic of
fingerprinting has been used for estimating the intra-voxel tissue component
fractions by resolving the equation Svoxel=Dw.
In this study, potential fractions of interested components are used for building
dictionary instead of T1 and T2, changing the solution of Svoxel =Dw into an optimization problem with
regularization terms. The results demonstrate that the proposed method could
provide more robust quantification of tissue composition and estimation of
partial volume effects.