Abstract #4377

Feasibility of Combining Perforating Artery Imaging and Whole Brain Vessel Wall Imaging at 7T

Zihao Zhang^1,2, Qi Yang^3,4, Zhaoyang Fan³, Xianchang Zhang^1,2, Yujiao Yang⁴, Jing An⁵, Zhentao Zuo¹, and Rong Xue^1,6

¹State Key Laboratory of Brain and Cognitive Science, Beijing MR Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, People's Republic of, ²Graduate School, University of Chinese Academy of Sciences, Beijing, China, People's Republic of, ³Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁴Xuanwu Hospital, Beijing, China, People's Republic of, ⁵Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, People's Republic of, ⁶Beijing Institute for Brain Disorders, Beijing, China, People's Republic of

In this study, we improved TOF-MRA and T1w-SPACE to a higher resolution for imaging perforating arteries and intracranial vessel walls at 7T. With the combination of the two techniques, we are for the first time able to depict the position of perforators and the vessel wall lesion in patients with ICAD. Small changes within the vessel wall may be revealed, and the certainty of the diagnosis may become better established, enabling better therapeutic management.

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