Abstract #4425

Variable Refocusing Flip Angle Single Shot Imaging For Anesthesia-Free Brain MRI

Kristen W. Yeom¹, Valentina Taviani¹, Andreas M. Loening¹, Michael Iv¹, and Shreyas S. Vasanawala¹

¹Stanford University, Stanford, CA, United States

Conventional single shot fast spin echo (SSFSE) and variable refocusing flip angle SSFSE (vrfSSFSE) were compared for fast sedation-free pediatric brain MRI (N=33). Two neuroradiologists independently and blindly evaluated SSFSE and vrfSSFSE images for motion, perceived resolution (sharpness), contrast and lesion conspicuity on a five-point scale. vrfSSFSE gave less motion and misregistration artefacts than conventional SSFSE, due to the shorter scan duration. As for the other image quality metrics, vrfSSFSE was found to be either comparable or superior to conventional SSFSE.

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