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Abstract #4426

Distortion correction of fetal EPI using registration of orthogonal stacks with Laplacian constraint

Maria Kuklisova Murgasova1, Georgia Lockwood Estrin1, Rita G. Nunes1,2, Mary Rutherford1, and Jo Hajnal1

1King's College London, London, United Kingdom, 2Instituto de Biofisica e Engenharia Biomedica, Faculdade de Ciencias, Universidade de Lisboa, Lisbon, Portugal

We present a novel method for correction of geometric distortions induced by static B0 field in fetal EPI. The method estimates distortion by including a distortion-correction step in the slice to volume reconstruction of orthogonal EPI stacks with orthogonal phase encoding directions, in the form of non-rigid registration with a Laplacian constraint. We show that the proposed method achieves better consistency with reconstructed ssFSE volumes than EPI volumes constructed from data corrected by B0 field map. The registration-based distortion correction is thus a viable alternative to acquisition of B0 field map.

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