Intracranial atherosclerotic enhancement on vessel wall MRI is associated with with symptomatic plaque, but there is insufficient data on the clinical characteristics associated with atherosclerotic enhancement on T1-weighted vessel wall MRI sequences or the relationship between atherosclerotic enhancement and recurrent stroke or TIA. Our study demonstrates that intracranial atherosclerotic plaque enhancement detected on 3T vessel wall MRI with 3D DANTE T1-SPACE accurately predicts a high risk of early stroke or TIA recurrence, with a potentially modifiable risk factor: elevated serum hemoglobin A1c.
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