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Abstract #0276

Characteristics of Morphology, Compositions and Distribution of Carotid Artery Atherosclerotic Plaques in Asymptomatic Elderly Population: A Three-Dimensional, Multicontrast Magnetic Resonance Vessel Wall Imaging Study

Ying Cai1, Le He2, Chun Yuan2,3, Huijun Chen2, Qiang Zhang2, Rui Li2, Cheng Li4, and Xihai Zhao2

1Department of Radiology, Yangzhou First People’s Hospital, Yangzhou, People's Republic of China, 2Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, People's Republic of China, 3Department of Radiology, University of Washington, Seattle, United States, 4Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, People's Republic of China

This study investigated the morphology, compositions and distribution of carotid artery atherosclerotic plaques in asymptomatic elderly population using 3D multicontrast MR vessel wall imaging. The atherosclerotic plaques were found to be prevalent (62.1%) and more than 12% subjects had high risk plaques (HRP) in this study population. Among carotid arteries without luminal stenosis, the prevalence of plaque and HRP was 43.2% and 8.3%, respectively. Benefiting from the 3D vessel wall imaging with large longitudinal coverage, near 14% of subjects had plaques in either distal ICA or proximal CCA segment which cannot be captured by traditional 2D vessel wall imaging.

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