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Abstract #0818

Initial experience with magnetic resonance elastography and acoustic radiation force impulse elastography in renal transplant patients

Paul Kennedy1, Octavia Bane1, Sonja Gordic1, Cecilia Besa1, Stefanie Hectors1, Mathilde Wagner1,2, Rafael Khaim3, Madhav Menon3, Vinay Nair3, Sara Lewis1, and Bachir Taouli1

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Radiology, Groupe Hospitalier Pitié Salpêtrière, Paris, France, 3Recanati Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

In this prospective study we compared renal transplant stiffness measured with MRE and ARFI ultrasound in 9 patients. Repeatability of both modalities was determined through test-retest imaging in 5 patients. MRE stiffness was significantly lower than ARFI stiffness as expected. MRE test-retest repeatability was excellent with mean coefficient of variation (CV) of 6%, while ARFI had CV of 30%. In addition, ARFI measurements exhibited a high inter-quartile range in the majority of cases suggesting inconsistency in the measurements. Our results suggest MRE is a more robust choice for renal transplant measurement compared to ARFI.

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