Precise localization of the epileptogenic zone and its delineation from eloquent cortex, are crucial for successful surgery. We propose analysis of macroscopic brain neural networks connectivity in the resting state and during the movement execution in patients with TLE for the possible epileptogenic macroscopic neural network localisation and motor cortex mapping. Our results show the concordant topography of the resting state network and the EEG epileptiform activity. Resting state fMRI could potentially depict the epileptogenic neural network in TLE which includes regions of temporal lobe and hippocampus. Motor network was shown to remain unaffected in TLE during interictal period.
