The current study aimed to use a novel graph-theory approach known as degree centrality to help diagnose methamphetamine abusers. Our findings identified increased degree centrality in right middle frontal gyrus, right inferior frontal gyrus and anterior cingulate cortex and degree centrality reductions were revealed in right superior parietal lobe and bilateral lingual gyrus. Additionally, decreased degree centrality of right lingual gyrus negatively correlated with the duration of methamphetamine abuse. Meanwhile, decreased degree centrality of right lingual gyrus might be a predictor of methamphetamine abuse duration with an acceptable diagnostic accuracy of 71%.
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