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Abstract #3200

Quantitative Assessment of Liver Fibrosis using MR-Phase Information

Motohira Mio1, Tetsuya Yoneda2, Kazuki Tani1, Tatsuo Toyofuku1, Toshihiro Maeda1, and Syoichi Morimoto3

1Department of Radiology, Fukuoka University Chikushi Hospital, Fukuoka, Japan, 2Department of Medical Physics in Advanced Biomedical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, 3Department of Radiology, Fukuoka University Hospital, Fukuoka, Japan

The aim of this study was to evaluate a potential of MR-phase information for a quantification of liver fibrosis. We measured phase value of the liver and examined the correlation between that value and the stage of fibrosis. Additionally, we also evaluate the correlations among phase value and the serum biomarkers of fibrosis and cirrhosis. The phase value showed high statistical correlation to stages of fibrosis, and to be linearly proportional to the following biomarkers; PLT, APRI, FIB-4 index. In conclusion, MR-phase information may is to be a noninvasive quantitative tool for liver fibrosis and its progression.

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