The hepatocyte fraction (HeF) is based on simple pharmacokinetics and can quantitatively estimate the fraction of hepatocyte. In our study, the HeF, quantitative liver-to-spleen contrast ratio (Q-LSC), and delta T1 value were compared and correlated with Child-Pugh and MELD score. The HeF demonstrated the highest correlations with Child-Pugh score (r = -0.58, P < 0.0001) and MELD score (r = -0.57, P < 0.0001). The HeF could be a useful biomarker for the evaluation of liver function, compared to conventional imaging based quantitative methods.
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