The quantitative measurement of the T2 relaxation time has been shown to be a useful tool for radiological diagnosis. However, the use of quantitative MRI (qMRI) in clinical routine is often hindered due to long acquisition times. Here, we assess T2 parameters in the lumbar and cervical spine as well as the knee using GRAPPATINI, a model-based accelerated T2 mapping sequence. Additionally, synthetic T2-weighted (T2w) images are derived from the quantitative maps. The T2 maps and synthetic T2w images are compared to conventional T2w and T2 mapping sequences, yielding an overall 5.8-fold time-saving.