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Abstract #5123

Effects of Load Induced Metabolic Changes of a Single Muscle on Whole Body Physiology

Kevin Moll1, Alexander Gussew1, Maria Nisser2, Steffen Derlien2, and J├╝rgen R. Reichenbach1

1Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 2Institute of Physiotherapy, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

31P MR spectroscopy enables a non-invasive evaluation of a metabolic response to a given exercise. A combination of this technique with other methods like 1H MRS, spirometry and blood lactate diagnostics improves the application field. Therefore, a broad range of metabolic parameters were acquired during an exercise of a single calf muscle to evaluate the effects of local energy demands on global parameters. We observed high adaptations resulting in good correlations between peripheral and locally measured values.

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