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Abstract #5278

Shared and Specific Intrinsic Functional Connectivity Patterns in Unmedicated Bipolar Disorder and Major Depressive Disorder

Ying Wang1, Junjing Wang2, Yanbin Jia3, Tao Liu3, Yao Sun1, Shuming Zhong3, Zhongping Zhang4, Li Huang1, and Ruiwang Huang2

1Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, 2Center for the Study of Applied Psychology & MRI Center,Center, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 3Department of Psychiatry, First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, 4MR Research China, GE Healthcare, Beijing

Our findings suggest that bipolar disorder (BD) and major depressive disorder (MDD) may have some shared and morespecific impairments of functional connectivity patterns during the depressiveperiod, providing new evidence for pathophysiology of BD and MDD at thelarge-scale whole brain connectivity level.

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