This study aimed to investigate the value of PET/MR 18F-NaF combined with CATCH technology in the diagnosis of high-risk plaque preliminarily. We compared if it had the statistical difference of PMR and TBRmax between the culprit vascular plaque and the control,and evaluated if it had correlation between PMR and TBRmax. There were higher PMR and TBRmax in culprit plaque. PMR and TBRmax had a weak correlation. PET/MR 18F-NaF combined with the CATCH technique can noninvasively determine the location of high-risk plaque in coronary artery, and is valuable for the diagnosis of high-risk plaque.