[Dy(EOB-DO3A)] is prepared according to the general
synthetic methods, and characterized by spectroscopic analysis.Therelaxivities
that measured at 9.4 T animal MRI are r1
= 1.01, r2 = 2.80 mM-1s-1.We
observe acceptablenegative-enhancement with liver T2-weighted image,
alsoconfirm about 30% liver accumulation within 1 h post-injection at
inductively coupled plasma (ICP) spectrometer data.