The ASL dynamics, the transit time to arterial and capillary, CBVa and CBF, were measured in control and mild cognitive impairment subjects to access cerebrovascular alteration in AD progression. The MCI subjects had prolonged transit time, lower CBVa and CBF in comparison to control subjects. Detailed aseesements of cerebrovascular alterations can provide better characterization of AD pathophysiology.
This abstract and the presentation materials are available to members only; a login is required.