Abstract #4191

New occurrences of macroscopic myocardial fibrosis in thalassemia at long term by multiple follow-up

Antonella Meloni¹, Vincenzo Positano¹, Laura Pistoia¹, Pietro Giuliano², Stefania Renne³, Riccardo Righi⁴, Priscilla Fina⁵, Petra Keilberg¹, Crocetta Argento⁶, Cristina Paci⁷, Antonella Massa⁸, and Alessia Pepe¹

¹Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, ²"ARNAS" Civico, Di Cristina Benfratelli, Palermo, Italy, ³Presidio Ospedaliero “Giovanni Paolo II”, Lamezia Terme, Italy, ⁴Ospedale del Delta, Lagosanto (FE), Italy, ⁵Ospedale "Sandro Pertini", Roma, Italy, ⁶Ospedale “San Giovanni Di Dio”, Agrigento, Italy, ⁷Ospedale “S Maria alla Gruccia”, Montevarchi (AR), Italy, ⁸Ospedale “Giovanni Paolo II”, Olbia, Italy

We investigated the evolution of myocardial fibrosis in terms of new occurrences over a period of 6 years in thalassemia patients who underwent to multiple LGE CMR scans and we detected an high number of new occurrences of myocardial fibrosis. Our data suggest the importance of repeating the LGE CMR over time using 'low risk' macrocyclic agents.

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