Three-dimensional reconstructions of cardiac magnetic resonance (CMR) datasets vary with contrast, image sequence, segmentation threshold, and manual post-processing. These influences need to be assessed before CMR-based models are used for interventional planning.
Three-dimensional segmentations of the right ventricular outflow tract (RVOT) from twelve patients with three different angiography sequences were compared between and within observers using different or the same thresholds.
Thresholding was sequence-dependent and did not significantly change object volumes. Minimal diameters of 3D reconstructed RVOTs showed clinically significant variation with different thresholds and between observers.
Interventional planning should rely on source images, not three-dimensional reconstructions, for quantitative information.