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Abstract #4782

Aortic 4D Flow MRI Data Analysis in Bicuspid Aortic Valve Disease in Under 15 Minutes

Amer Ahmed Syed1, Daniel Zachary Gordon1, Jeremy D Collins1, Alireza Sojoudi2,3, Qiao Wei2, Xuexin Gao2, Michael B Scott1, Bradley D Allen1, James C Carr1, and Michael Markl1,4

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Circle Cardiovascular Imaging Inc., Calgary, AB, Canada, 3Circle Cardiovascular Imaging, Calgary, AB, Canada, 4Department of Biomedical Engineering, Northwestern University, Evanston, IL, United States

One of the main challenges to the efficient application of 4D flow MRI is related to cumbersome, time-consuming, and non-standardized data analysis. The purpose of this study was to test the efficiency and inter-observer reproducibility of a dedicated analysis workflow by using a 4D flow MRI tool in a cohort of 20 BAV patients. We showed that 4D flow MRI can visualize BAV mediated changes on aortic outflow and quantify associated changes in flow dynamics. We demonstrated the potential of an optimized data analysis workflow to perform standardized 4D flow MRI processing in a short time and with good-to-excellent reproducibility.

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