Working memory is a critical cognitive function implicated after mild traumatic brain injury (MTBI). Here, we investigate the association between white matter microstructure and working memory in normal controls (NC) and MTBI patients, using diffusion white matter tract integrity (WMTI) and WAIS-IV subtests, respectively. For the NC group, significant correlations were observed in axonal water fraction (AWF; higher axonal density/myelination) and mean kurtosis (MK; greater tissue complexity) with letter-number sequencing (LNS). However, such relationships were not present in the MTBI group.
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