Abstract #5107

Chemical Exchange Saturation Transfer imaging of prostate cancer at 3T: Repeatability, and initial results of an acquisition and multi-pool analysis protocol

Vincent Evans¹, Francisco Torrealdea¹, Marilena Rega², Mina Kim³, Mrishta Brizmohun Appayya¹, Arash Latifoltojar¹, Shonit Punwani¹, Xavier Golay³, and David Atkinson¹

¹Centre for Medical Imaging, UCL, London, United Kingdom, ²Institute of Nuclear Medicine, UCLH, London, United Kingdom, ³Brain Repair and Rehabilitation, Institute of Neurology, UCL, London, United Kingdom

An optimised acquisition and post-processing protocol for multi-pool Lorentzian analysis of CEST data in the prostate at 3T is described. The repeatability of the technique is evaluated in five healthy volunteers and the contrast observed between healthy tissue, TZ tumour and PZ tumour in two prostate cancer patients is evaluated.

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