Creativity is taken as a spontaneous mental process and creativity scales associates with resting-state functional connectivity in literature. However, it remains unclear that how brain integrity changes following creative thoughts. Targeting on this causal effect, we explored the functional connectivity before and after the engagement of divergent thinking. We demonstrated the interactions between brain activations in divergent thinking and functional connectivity in certain networks, especially in the locus of left inferior frontal gyrus (IFG). Meanwhile, the reduced IFG-precuneus connections could benefit the creativity performances.