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Abstract #0604

Multi-shot DWI with multiplexed sensitivity encoding (MUSE) versus single-shot DWI in the breast

Yuxin Hu1, Arnaud Guidon2, Lloyd Estkowski3, Bruce Daniel4,5, Brian Hargreaves1,4,5, and Catherine Moran4

1Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 2Global MR Application and Workflow, GE Healthcare, Boston, MA, United States, 3Global MR Application and Workflow, GE Healthcare, Menlo Park, CA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States, 5Department of Bioengineering, Stanford University, Stanford, CA, United States

Diffusion-weighted imaging (DWI) has shown strong potential for clinical impact in breast MRI but is limited by low resolution and image distortion. Multi-shot acquisitions can help to address these limitations. Here we assess a multi-shot diffusion acquisition utilizing two different reconstructions in comparison to single-shot DWI in breast cancer patients. The assessment includes quantified perceived resolution and ratings of qualitative image characteristics with respect to the DCE-MRI acquisition.

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