The mdx mouse model is one of the most commonly used animal models for Duchenne muscular dystrophy (DMD). Although the mdx model has a milder phenotype compared to patients with DMD, the model has shown the similarity in some histopathologic events resulting in wide utilizations in preclinical studies for both disease progression and therapeutic intervention. Over the years MRI has been increasingly being utilized to monitor the disease progression in dystrophic mice and DMD patients. We performed MRI to discriminate the time course of damage in regeneration in skeletal muscles if mdx mice.
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