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Abstract #1709

Partial velocity-compensated optimized diffusion encoding for combined motion compensation and residual vessel signal suppression in liver ADC mapping

Sean McTavish1, Anh Tu Van1, Johannes Peeters2, Tetsuo Ogino3, Andreas Hock4, Ernst Rummeny1, Rickmer Braren1, and Dimitrios Karampinos1

1Technical University of Munich, Munich, Germany, 2Philips Healthcare, Best, Netherlands, 3Philips Healthcare, Tokyo, Japan, 4Philips Healthcare, Hamburg, Germany

Despite its strong clinical significance in lesion detection and tumor staging, liver DWI remains challenged by its strong sensitivity to motion effects. Motion-compensated diffusion encoding schemes have recently been proposed to improve DW liver signal homogeneity especially in the left liver lobe, a region typically affected by cardiac motion. However, motion-compensated diffusion encoding is associated with hyperintense vessel signal even at high b-values, which can obscure lesion detection. The present work proposes a partial velocity-compensated diffusion encoding using asymmetric diffusion gradients for combined motion compensation and residual vessel signal suppression in liver DWI, optimized for short echo times.

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